The OpenSLS system established by bioengineerers enables 3D printing technology to be used in biomedical research

Bioengineering researchers at Rice University in the United States have modified a commercial grade CO2 laser cutting machine to create an open source selective laser sintering (SLS for complex plastic 3D objects using plastic powders and biomaterials). Selective laser sintering, OpenSLS) platform. This system allows researchers to take advantage of the specific materials that meet their needs, and the cost of building the system is very low, less than $10,000, which is at least 40 less than the industry's usual capital ($400,000 to $1 million). Times. The design and operational performance of the device was published in PLOS ONE.

Let 3D printing technology be used in biomedical research

SLS technology has been around for more than 20 years and is a type of 3D printing technology that can produce objects with bifurcated or suspended protruding structures. Co-author of the study, Jordan Miller, an assistant professor of bioengineering at Rice University, who specializes in applying 3D printing to tissue engineering and regenerative medicine, said: "SLS technology can perfectly create the complex shapes we need for our work, such as vascular networks. , liver or other organs."

The traditional 3D printing is a 2D flat pattern drawn by a pinhole spray-thawed plastic and then layered into a 3D structure. The difference between the OpenSLS system and the traditional 3D printing is that the SLS laser is directly applied to the flattened plastic powder base, and after the powder on the laser focus is heated, it is melted and sintered to form a solid adhesion. In this way, by changing the position of the laser, a single-layer solid structure can be produced.

Miller described the process as a bit like a baking bud. The chef would sprinkle a layer of powdered sugar and then heat it with a torch to bond them together to form a hard outer skin. In the case of SLS, the powdered sugar was replaced with powder. Shaped biomaterial, the heat source is replaced by laser light.

After the construction of the finished layer is completed, a new layer of material powder is placed, which is also treated by laser, and the complete structure can be produced by repeating several times. Because SLS is always covered in the powder of material during the manufacturing process, it can make some particularly complicated structures that other 3D printing cannot.

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