On January 9th, a joint research team led by Kakuda Kakuhiko of the Japanese Institute of Physical Chemistry conducted a large-scale genome-wide association analysis to discover new asthma-related genes, the relationship between asthma and autoimmune diseases and inflammatory diseases, and the involvement of immune responses. A clue to the infection. The prevalence of multifactorial disease asthma is 5% to 8% in the Japanese; in the United States, 3.9% for Mexicans and 12.5% ​​for Africans. In asthma patients, the contribution rate of genetic factors is estimated to be about 25% to 80%. The difference between the prevalence rate and the estimated contribution rate is so great because asthma is easily affected by the environment and the symptoms vary widely. Only 21 of the asthma-related loci have been discovered in the past 20 years. To find new asthma-related genes, researchers from various countries have established the Transnational Asthtic Genetics Association (TAGC). Using the TAGC data, the team analyzed data from 142,000 people and constructed a comprehensive catalog of 18 asthma risk loci and 878 single nucleotide polymorphisms (SNPs) that were not susceptible to human and environmental impact, and found 5 A new asthma risk locus and new asthma-associated SNPs were identified in two known loci associated with asthma and hay fever complications. By combining these asthma-related SNP lists with known databases, the researchers found that autoimmune diseases and inflammatory disease-associated SNPs have a large overlap. At the same time, asthma-related SNPs are concentrated near the enhancer of immune cells and may be responsible for immune-related control functions. In the future, the research team will study the detailed mechanism of asthma, and hope to develop effective therapeutic drugs for asthma by discovering molecular targets. It is also expected to use the newly discovered SNP population as a genetic marker to predict the risk of asthma. (Technology Daily) Shampoo,Dry Shampoo,Dandruff Shampoo,Head And Shoulders Shampoo Guangzhou Lingxue Cosmetics Co., Ltd , https://www.gzlxgj188.com