Rongcheng Jingyi Oceanic Technology Company Limited , https://www.jingyifoods.cn
1Structure and performance of straight-type extraction tank 1.1 The structure of the straight-type extraction tank is as follows: The straight-type extraction tank (shown in Figure 1) adopts the full-body form of the inner tank body, which is the common structural form of the extraction tank, and the slag discharge part is generally adopted. The ring lock device has dual cylinder control and is safer than the traditional lock device. Since the tank structure is thin and long, and is limited by the size of the slag door, the height of the tank is required for the height of the plant. At present, most of the straight-type extraction tanks produced by equipment manufacturers have various specifications ranging from pilot equipment to production equipment ranging from 50L to 6m3. In addition to the main extraction tank, accessories such as foam separation, condenser, cooler, oil-water separator and filter are available for extraction of aromatic oil and recovery of solvent. The parts of the main extraction tank and accessories and the materials are made of stainless steel, and the slag door is equipped with a stainless steel mat filter. The opening and closing and locking of the slag door are controlled by the cylinder. In order to ensure the normal operation of the slag, the required compressed air of the cylinder is required to be 0.6-0.7 MPa, and the control of the gas path can be matched according to the requirements of the user. Usually, traditional Chinese medicine manufacturers should also allocate auxiliary vacuum pumps, air compressors and other auxiliary facilities. These devices occupy a critical initial stage in the entire process of extracting and refining Chinese medicines.
1.2 Performance characteristics of straight-type extraction tanks (1) The equipment is suitable for traditional Chinese medicine preparation enterprises, health care products production enterprises and natural medicine extract enterprises, such as normal pressure, pressurized water decoction, heat reflux and temperature for Chinese herbal medicines and other plants and animals. Various processes such as dip, forced circulation seepage, extraction of aromatic oil and recovery of organic solvent.
(2) The main body adopts a straight-tube structure, which makes feeding and discharging slag extremely easy and convenient.
(3) The slag door adopts ordinary double cylinder closing or three cylinder clamp rotating type. The clamp rotary slag door adopts single cylinder to close and close, the double cylinder rotates to push the clamp, and the air pressure seal completely solves the leakage or decoupling accident caused by the unstable pressure of the compressed air source. The safety factor is high and the sealing performance is good. .
(4) The parts in contact with the equipment are made of stainless steel, the outer surface is polished or frosted, and the tank is equipped with CIP system, which meets GMP requirements. Can be combined into a dynamic extraction system.
2 common straight-type extraction tank product specifications The common straight-type extraction tank product specifications are shown in Table 1.
(2) Countercurrent forced circulation operation, with an outlet in the middle of the tank, pumping the extract into the bottom of the tank lid with an infusion pump to form a pressure-type upward push, which has both a circulation effect and a better loosening of the medicine in the tank, greatly increasing Extraction efficiency. However, the setting of the central export is relatively critical, and because of the different Chinese herbal medicines, the nature of the drugs is different, which makes the selection of the location of the intermediate outlets more difficult. Some enterprises adopt activity exits, but the seals that are prone to activity exits are not well handled, and liquid leakage is serious.
(3) Dynamic extraction is to add a deceleration agitator at the top of the bottom of the tank. The medicinal material is decocted in the tank and stirred in the middle. The design and use requirements of the position, size, function and sealing of the agitator are higher.
(4) The extraction process adopts these three aspects, which has the advantages of short time, high speed and high liquid content. When the aromatic oil is extracted, after the secondary steam passes through the condensation and cooling, the oil water enters the oil water separator, the light oil is discharged at the upper part of the separator, the heavy oil is discharged at the lower portion, and the water is discharged or recirculated through the overflow. At the end of the boiling, it is necessary to carry out vacuum discharge, which not only shortens the liquid discharge time, but more importantly, it can exhaust the effective residual liquid in the slag and avoid waste.
(5) When the equipment is in working condition, the valve of the air circuit of the upper hook locking system is also in working state. The working cylinder must be used to prevent the pressure from being decoupled and an accident occurs.
(6) Extraction heating temperature is not uniform, especially in the case of water extraction, in general, in addition to temperature requirements, the actual application of Chinese herbal medicines is mainly based on the boiling state of the liquid surface, which is evident in this type of extraction tank. For example, when the Chinese herbal medicine is extracted with water, if it is a heavy material such as rhizomes or minerals, it is deposited in the lower part of the tank during extraction, and the extract is in the upper middle part of the medicine, during the heating process, due to the saponin contained in the Chinese herbal medicine. The composition is prone to foam, which causes the surface to be severely boiling, but the temperature of the actual medicinal material is very low, and the effect of extracting the active ingredient is not at all achieved.
(7) Equipment design and installation error, the general extraction tank heating part is divided into 2 to 3 parts, each part can be controlled separately for heating, some equipment installation enterprises in order to save costs, the heating part is connected in series during construction, only installed A valve is used to control, which in turn leads to waste of incomplete extraction.
(8) Operation error, all heating devices should be turned on when the equipment starts to use heating operation. When reaching a certain temperature, the upper heating device should be turned off, and only the heating device at the bottom of the zui is kept, so as to ensure that all the extraction liquid is heated, and the extraction is avoided as much as possible. The occurrence of a false boiling of the liquid.
(9) Equipment application expansion, in addition to the conventional boiled extraction, the equipment can also be applied to extract volatile oil, countercurrent extraction, and a better application is the extraction of Chinese medicine, and the recovery of ethanol. If the company has a number of similar equipment, it is possible to install a new extraction process such as countercurrent extraction during the installation of the equipment, which is convenient for updating and improving the drug extraction process.
4 Precautions when using the straight-type extraction tank (1) It is strictly forbidden to play with the handle of the feeding port before the pressure operation or the residual pressure in the equipment has not been relieved. When closing the feed port, the locating pin must be inserted into the hook groove. The tank filling and liquid addition must check whether the slag door safety cylinder is in the locked insurance state.
(2) After the operation of the pneumatic components of the extraction tank is completed (after opening and closing the slag door), the operator should close the intake main valve in time to avoid the fatigue deformation of the tank due to the long-term action of the higher pressure air.
(3) When extracting alcohol, the workshop design must comply with the explosion-proof standard. Smoking and other open flames must be absolutely prohibited in the workshop. When operating the alcohol, the vacuum operation is used, or the condenser and the cooler are cooled and then flow into the tank. The pump cannot be forced to circulate.
(4) Slowly open the steam valve when using the steam to enter the jacket. The pressure should not exceed 0.2 MPa. The pressure relief valve, safety valve and pressure gauge must be installed during installation.
(5) After use, the tank should be cleaned and dried for the next production and use.
5 Conclusion details are the key parts of equipment manufacturing and use. This article starts with the structural characteristics of the equipment, the subtle problems in the production application, analyzes in detail the details of the equipment use, and combines some new regulations and equipment for the pharmaceutical machinery. The common problems in use fully analyze the personality characteristics of these devices, and provide some reference for how the pharmaceutical equipment manufacturers can better serve the pharmaceutical manufacturers, how to better facilitate the modernization of traditional Chinese medicine preparations, and also facilitate the production of pharmaceutical enterprises. When applying these devices, you can avoid weaknesses and avoid unnecessary losses.
Analysis of Advantages and Disadvantages of Straight Extraction Cans in Extraction of Traditional Chinese Medicine Preparations
The production process of modern Chinese medicine preparations is inseparable from the extraction of Chinese herbal medicines, and the use of compound preparations according to the theory of traditional Chinese medicine is a distinctive feature of traditional Chinese medicines. How to extract the effective parts or active ingredients and auxiliary ingredients of each constituent medicine in the compound as much as possible. Invalid ingredients and tissue materials are not extracted as much as possible, which is closely related to the choice of extraction equipment and how to properly apply these equipment. In this paper, the extraction equipment commonly used in the traditional Chinese medicine preparation enterprises, the common problems in the actual production of straight-type extraction tanks and the application of equipment expansion in the production of traditional Chinese medicine preparations, are introduced for the selection of equipment for Chinese medicine preparation manufacturers. And reference to the transformation.
Table 1 Common Straight Extraction Tank Product Specifications
3 Advantages and disadvantages of straight-type extraction tanks in extraction and production applications (1) Down-flow forced circulation operation, using the infusion pump installed at the bottom outlet of the tank to extract the Chinese medicine liquid, sprinkle it from the top of the extraction tank, so that the medicine is effective The ingredients are extracted. The common problem with zui is that under the action of water pressure, the Chinese herbal medicines are getting tighter and tighter, which leads to the inability of the extract to pass through the medicine and does not form an effective concentration gradient and leads to blockage. Moreover, the straight type has a small inner diameter and is not suitable for agitator. Specification model
TQ-T-1.0
TQ-T-2.0
TQ-T-3.0
TQ-T-6.0
Volume / L
1 200
2 300
3 200
6 300
In-tank design pressure / MPa
0.09
Sandwich design pressure / MPa
0.3
Compressed air pressure / MPa
0.6 to 0.7
Feeding port diameter / mm
400
400
400
500
Heating area / m 2
3.0
4.6
6.0
7.5
Condensation area / m 2
4
4
5
5
Cooling area / m 2
1
1
1
2
Filtration area / m 2
3
3
3
5
Slag door diameter / mm
800
800
800
1 000
Energy consumption / kg / h
240
340
340
640
Equipment weight / kg
1 800
2 400
2 400
3 000