Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

Model NO.: Follistatin 315
Water Content(Karl Fischer): 5.0%
Acetate Content(by HPLC): 15.0%
Trademark: DMK
Transport Package: Aluminum Foil Bag/Carton
Specification: API
Origin: China
HS Code: 29061310
Model NO.: Follistatin 315
Water Content(Karl Fischer): 5.0%
Acetate Content(by HPLC): 15.0%
Trademark: DMK
Transport Package: Aluminum Foil Bag/Carton
Specification: API
Origin: China
HS Code: 29061310
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

What is Follistatin 

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it. 

Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.

Follistatin (FS) was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FS is a high-affinity activin-binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid (aa) residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh).
***************************************************************************
Specification: 1mg/vial
Purity: 98%min
Appearance: White powder
Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
Water Content(Karl Fischer): ≤5.0%
Acetate Content(by HPLC): ≤15.0%
Amino Acid Composition: ±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC): ≤1.0%
Peptide Content(by %N): ≥80%
Assay(By Anhydrous, Acetic Acid-free ): 95.0~105.0%
Bacterial Endotoxins : ≤5EU/mg
Storage/Stability: Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended.
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

***************************************************************************
Follistatin 315 (FST-315):

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle?stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an N?terminal atypical TGF binding domain, three Follistatin domains that contain EGF?like and kazal?like motifs, and a highly acidic C?terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.

***************************************************************************

Application of Follistatin
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .

Follistatin and Muscle Growth:
Follistatin works by binding to and inhibiting transforming grow factor- (TGF-) peptides such as myostatin which is responsible for regulating and limiting muscle growth.  It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow. In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function.However, FSH levels that are too low can also negatively impact health and reproductive capabilities.
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

***************************************************************************
Related Product:
Peptides Specification Peptides Specification
MGF 2mg/vial Halodrol Customized
PEG MGF 2mg/vial Argreline Acetate Customized
CJC-1295 with DAC 2mg/vial Angiotensin Customized
CJC-1295 without DAC 2mg/vial Lanreotide Customized
PT-141 10mg/vial Arelin Acetate powder
Melanotan I  10mg/vial Carbetocin Acetate Customized
Melanotan II 10mg/vial Copper peptide(GHK-Cu) Customized
GHRP-2 5mg or 10mg/vial Acetyl tetrapeptide-5 Customized
GHRP-6 5mg or 10mg/vial Terlipressin Acetate Customized
Ipamorelin 2mg/vial SNAP-8 Customized
Hexarelin 2mg/vial Exenatide acetate Customized
Sermorelin 2mg/vial Fertirelina Customized
Oxytocin 2mg/vial Octreotide acetate Customized
TB500 2mg/vial Argipressine Customized
pentadecapeptide BPC 157 2mg/vial Goserelin acetate Customized
  2mg/vial Decapeptide-12 Customized
Triptorelin 2mg/vial EYESERYL Customized
Tesamorelin 2mg/vial Thymosin α1 Acetate Customized
Gonadorelin 2mg or 10mg/vial Serilesine Customized
DSIP  2mg/vial Palmitoyl Tetrapeptide-7 Customized
Selank 5mg/vial   Customized
AOD-9604 2mg/vial Palmitoyl Tripeptide-5 Customized
Adipotide 2mg/vial Palmitoyl Pentapeptide Customized
ACE 031 1mg/vial Myristoyl-Pentapeptide-17 Customized
GDF-8 1mg/vial Acetyl tetrapeptide-5 Customized
Thyrotropin TRH powder Acetyl Glutamyl Heptapeptide-3 Customized
Epitalon 10mg/vial Palmitoyl Tripeptide-1(Pal-GHK ) Customized
Follistatin 344 1mg/vial Nesiritide Acetate Customized
Follistatin 315   1mg/vial Eptifibatide Customized
Deslorelin  20mg/vial Desmopressin acetate Customized
Nonapeptide-1 1mg/vial Teriparatide acetate Customized

Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
3. How to cooperate with us?
You can contact us for cooperation through the website contact information, or contact with the salesmen in our company. We will connect you about the specific detail via email. 

Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept T/T  , Moneygram , Western Union.

Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
    For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8  How to proceed order?
Let me konw the items,quantity and the destination contury wihch help me to give you a right price
Please let me know the items you are looking for, quantity and the destination country.After you confirm all details of order, pay money 100% in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.

Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

What is Follistatin 

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it. 

Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.

Follistatin (FS) was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FS is a high-affinity activin-binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid (aa) residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh).
***************************************************************************
Specification: 1mg/vial
Purity: 98%min
Appearance: White powder
Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
Water Content(Karl Fischer): ≤5.0%
Acetate Content(by HPLC): ≤15.0%
Amino Acid Composition: ±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC): ≤1.0%
Peptide Content(by %N): ≥80%
Assay(By Anhydrous, Acetic Acid-free ): 95.0~105.0%
Bacterial Endotoxins : ≤5EU/mg
Storage/Stability: Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended.
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

***************************************************************************
Follistatin 315 (FST-315):

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle?stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an N?terminal atypical TGF binding domain, three Follistatin domains that contain EGF?like and kazal?like motifs, and a highly acidic C?terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.

***************************************************************************

Application of Follistatin
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .

Follistatin and Muscle Growth:
Follistatin works by binding to and inhibiting transforming grow factor- (TGF-) peptides such as myostatin which is responsible for regulating and limiting muscle growth.  It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow. In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function.However, FSH levels that are too low can also negatively impact health and reproductive capabilities.
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

***************************************************************************
Related Product:
Peptides Specification Peptides Specification
MGF 2mg/vial Halodrol Customized
PEG MGF 2mg/vial Argreline Acetate Customized
CJC-1295 with DAC 2mg/vial Angiotensin Customized
CJC-1295 without DAC 2mg/vial Lanreotide Customized
PT-141 10mg/vial Arelin Acetate powder
Melanotan I  10mg/vial Carbetocin Acetate Customized
Melanotan II 10mg/vial Copper peptide(GHK-Cu) Customized
GHRP-2 5mg or 10mg/vial Acetyl tetrapeptide-5 Customized
GHRP-6 5mg or 10mg/vial Terlipressin Acetate Customized
Ipamorelin 2mg/vial SNAP-8 Customized
Hexarelin 2mg/vial Exenatide acetate Customized
Sermorelin 2mg/vial Fertirelina Customized
Oxytocin 2mg/vial Octreotide acetate Customized
TB500 2mg/vial Argipressine Customized
pentadecapeptide BPC 157 2mg/vial Goserelin acetate Customized
  2mg/vial Decapeptide-12 Customized
Triptorelin 2mg/vial EYESERYL Customized
Tesamorelin 2mg/vial Thymosin α1 Acetate Customized
Gonadorelin 2mg or 10mg/vial Serilesine Customized
DSIP  2mg/vial Palmitoyl Tetrapeptide-7 Customized
Selank 5mg/vial   Customized
AOD-9604 2mg/vial Palmitoyl Tripeptide-5 Customized
Adipotide 2mg/vial Palmitoyl Pentapeptide Customized
ACE 031 1mg/vial Myristoyl-Pentapeptide-17 Customized
GDF-8 1mg/vial Acetyl tetrapeptide-5 Customized
Thyrotropin TRH powder Acetyl Glutamyl Heptapeptide-3 Customized
Epitalon 10mg/vial Palmitoyl Tripeptide-1(Pal-GHK ) Customized
Follistatin 344 1mg/vial Nesiritide Acetate Customized
Follistatin 315   1mg/vial Eptifibatide Customized
Deslorelin  20mg/vial Desmopressin acetate Customized
Nonapeptide-1 1mg/vial Teriparatide acetate Customized

Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity
Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
3. How to cooperate with us?
You can contact us for cooperation through the website contact information, or contact with the salesmen in our company. We will connect you about the specific detail via email. 

Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept T/T  , Moneygram , Western Union.

Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
    For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8  How to proceed order?
Let me konw the items,quantity and the destination contury wihch help me to give you a right price
Please let me know the items you are looking for, quantity and the destination country.After you confirm all details of order, pay money 100% in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.

Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity

Top Grade &Freeze-Dried Injection Peptides Follistatin 315 Powder with 99% Purity