Nano medical device research and development into the fast lane into a development focus

Release date: 2008-07-24

Nano-medical device research and development into the fast lane into development, the development of nano-silver new coatings will be “wearing” a thin coat with effective antibacterial effect for various medical devices, which can greatly reduce the cross-infection of patients during hospital treatment. Risk, saving on treatment costs.
Nano is a unit of length (meaning one billionth of a meter). Nanomaterials have many properties not found in conventional materials. Nanomaterials have been widely used in various industrial fields to date. Of course, medical devices are no exception. "Nanomedical devices" have become the focus of development of new products in the 21st century international medical industry.
The term "nanomedical device" refers to a medical device assembled using components processed by nanomaterials; or a medical device or surgical instrument coated with a nanomaterial surface. According to the US "Nano Biotechnology News" weekly report, at least 60 new drug preparations and 90 new medical devices, diagnostic reagents and other new products have been used in the United States. With more and more orthopedic materials, cardiovascular implants (such as vascular stents, etc.), surgical instruments and other improved products coated with new nanomaterials, experts predict that the US nano medical device market sales The amount will increase from 400 million US dollars in 2006 to 5.2 billion US dollars in 2011. The development of new nanomedical device products has entered the fast lane with the development of technology, and its vision is desirable. Nano medical devices are a brand-new product for China's medical device industry. It is necessary for medical device practitioners in China to understand the advanced experience of foreign countries as a new goal for our study or imitation development.
New nano-coating with antibacterial effect
According to the latest report of the National Center for Disease Control, in the past few years, 2 million patients in the country were infected with bacteria during hospital treatment, resulting in treatment costs of up to 4.8 billion US dollars. It is understood that a large part of hospital infections are caused by microorganisms remaining on surgical instruments that are not thoroughly disinfected.
Not long ago, I-FLOW Biomaterials Inc. of the United States listed the "Nano Silver" series of sterile catheters containing the company's patented technology. The principle is to apply a thin layer of nano-scale silver ions on the surface of ordinary polypropylene medical catheters. Silver is known to be the best natural antibacterial material. The successful development of nano silver new coatings will “wear” a thin outer coat with effective antibacterial effect for various medical devices, which can greatly reduce the risk of patients being cross-infected during hospital treatment and save treatment costs. It is reported that the US FDA has officially approved the company's new nanosilver sterile catheter products for clinical use in May this year.
New medical fiber for nanomaterials
Researchers at Ohio State University have developed a new nanomaterial that can be used for surface treatment of common medical fiber fabrics. The medical fiber fabric treated by this nano material has waterproof and oil-proof properties, and more importantly, it has a magical "self-cleaning" ability. Therefore, it can prevent microbial contamination and prevent cross infections that are common in hospitals. The nano medical fiber fabric can be processed into surgical towels, doctor/nurse work clothes and work hats, patient clothes, bed sheets and other common medical textiles. Its market prospects are very broad.
Nanoscale micromotor
According to the latest foreign reports, Professor Wang Zonglin, a Chinese-American scientist in the Department of Materials Science at the Georgia Institute of Technology, and his assistant have developed a miniature nano-motor. The magic of a miniature nanomotor is that it draws energy from the surrounding environment and converts it into electricity. According to Wang Zonglin, the nano-motor is made by first growing a gallium arsenide at a distance of half a nanometer on a soft polymer substrate, and then "long" the zinc oxide on the surface. In order to collect current. Such a semiconductor micro-motor uses a piezoelectric effect to generate an average current of 4 W per square centimeter in a living organism. Nanomotors can be installed as power sources in implantable medical devices and implantable drug pumps such as pacemakers and ventricular defibrillators. In theory it can be used indefinitely (unless the parts are aging). Once put into production, such nano-micromotors will fundamentally change existing medical devices, especially implantable devices.
Pocket disease diagnostic apparatus
This is a pocket disease diagnostic device that can be placed in a pocket. The key component is a silicon chip that can only be used once, but at a very low price. According to reports, the surface of the chip is coated with a thin layer of microporous membrane made of nano material, which can simulate the filtration system of human cells. As long as the user squeezes a drop of blood on the chip, the handheld disease diagnostic device can quickly determine whether there is any disease. The instrument can correctly interpret a variety of diseases such as hepatitis B, HIV (AIDS), diabetes and even certain tumor diseases according to blood samples. Its advent is a new development in medical diagnostics. Even those patients who do not understand the professional laboratory knowledge, as long as a drop of blood according to the instrument operating instructions can get a preliminary understanding of their health.
Nanoscale light source
The Lawrence Berkeley National Laboratory, part of the US Department of Energy, recently developed a "bio-friendly nanoscale light source" that emits visible light. This nanoscale source has many uses, such as "single cell endoscopy" and "secondary wave bioimaging technology". Nano-scale light sources are expected to have broad application prospects in future medical device new products.
Remote control "nanomachinery"
Researchers at the University of California, Berkeley invented one of the world's smallest remotely operable nanomachines. According to reports, it is to stick a molecule of the organic compound "azobenzene" on the gold powder, as long as it is irradiated on the azobenzene molecule with an ultraviolet laser to force them to change their original shape. University of California researchers envisioned that their remotely-operable nanomachines could be used in switches, pistons or other moving parts in the future, and in turn to develop ultra-small medical devices that can be operated remotely.
Other new nanoscale medical device products in clinical research include: a retinal implantable nanomaterial that restores vision to many blind people who are blind due to "retinitis" eye disease. The blind person can see the external image by wearing a pair of special glasses (the camera has a miniature camera). The working principle is that the miniature camera will take the external image into the retina and implant it into the nano material and convert it into a bio-current signal, which will be transmitted into the visual center of the brain and form an image, so that the blind can see the real external image. . This complex blind visual recovery medical device is still being tested, and once it goes on the market, it will bring the gospel to millions of blind people around the world. Another new nanomedical device under test is “Nano-coated dental material”, which has strong antibacterial activity, prevents oral microbes from adhering to gums and teeth, and has self-purifying ability.
All in all, medical devices made of new nanomaterials will change the old appearance of existing medical device products and become a new bright spot in the 21st century medical device market, and its development prospects are broad and broad. ——Shanghai Medical Device Industry Association website

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